Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation

Bowen Wu, Tuantuan Zhao, Ke Jin, +5

Nature Immunology

InflammationAutoimmune DiseaseMitochondrial FunctionImmunologyAutophagy +5

Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline

Hongtao Wang, Fulian Huang, Zhao‐Lan Hu, +6

Neurotoxicity Research

Rats ResultsEarly Life StressPsychoneuroimmunologyPsychiatryBehavioral Neuroscience +11

Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus

Wenyu Cao, Juan Duan, Xueqin Wang, +9

Behavioural Brain Research

Molecular NeuroscienceNeurobiological FactorAdult RatNeuropharmacologyNeurology +6

Aging-associated HELIOS deficiency in naive CD4+ T cells alters chromatin remodeling and promotes effector cell responses

Huimin Zhang, Rohit R. Jadhav, Wenqiang Cao, +9

Nature Immunology

Aging-associated Helios DeficiencyChromatinCell ResponsesChromatin RemodelingT-regulatory Cell +6

Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress

Yanwei Luo, Yang Xu, Wenyu Cao, +9

Neuropharmacology

Chronic StressPsychoneuroimmunologyGrowth HormoneStress HormonePsychiatry +12

The transcription factor RFX5 coordinates antigen-presenting function and resistance to nutrient stress in synovial macrophages

Zhao‐Lan Hu, Tuantuan Zhao, Tao Huang, +9

Nature Metabolism

InflammationAutoimmune DiseaseTranscription Factor Rfx5Adaptive Immune SystemImmune Cell Development +11

ProBDNF promotes sepsis-associated encephalopathy in mice by dampening the immune activity of meningeal CD4+ T cells

Ru‐Yi Luo, Cong Luo, Feng Zhong, +4

Journal of Neuroinflammation

Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats

Feng Zhong, Lei Liu, Jiali Wei, +8

Frontiers in Psychiatry

Neurobiological MechanismStress HormonePsychiatryBehavioral NeuroscienceNeurobiological Factor +11

MicroRNA-29a plays a suppressive role in non-small cell lung cancer cells via targeting LASP1

Zhao‐Lan Hu, Yanhui Cui, Yanhui Zhou, +4

OncoTargets and Therapy

AKF-PD alleviates diabetic nephropathy via blocking the RAGE/AGEs/NOX and PKC/NOX Pathways

Jiao Qin, Zhangzhe Peng, Qiongjing Yuan, +10

Scientific Reports