Molecular markers of early Parkinson's disease based on gene expression in blood

Clemens R. Scherzer, Aron C. Eklund, Lee Jae Morse, +12

Proceedings of the National Academy of Sciences

GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein

Clemens R. Scherzer, Jeffrey A. Grass, Zhixiang Liao, +9

Proceedings of the National Academy of Sciences

Neurodegenerative DiseasesTranscriptional RegulationMolecular NeuroscienceGata Transcription FactorsGenetics +12

Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts

Ganqiang Liu, Joseph J. Locascio, Jean‐Christophe Corvol, +127

The Lancet Neurology

Neuroimaging BiomarkersNeurodegenerative DiseasesCognitive ScienceLongitudinal AnalysisNeuropsychological Functioning +7

The Wnt-inducible Transcription Factor Twist1 Inhibits Chondrogenesis

Martina I. Reinhold, Ravi M. Kapadia, Zhixiang Liao, +1

Journal of Biological Chemistry

Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease

Ganqiang Liu, Jiajie Peng, Zhixiang Liao, +29

Nature Genetics

Neuroimaging BiomarkersNeurodegenerative DiseasesSynaptic PlasticityPolygenic ScoreGenetics +9

Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

Xianjun Dong, Zhixiang Liao, David Gritsch, +19

Nature Neuroscience

NeuropsychologyPsychiatryGeneticsPsychiatric GeneticsGenetic Factor +9

Transcriptional modulator <i>H2A histone family, member Y</i> ( <i>H2AFY</i> ) marks Huntington disease activity in man and mouse

Yi Hu, Vanita Chopra, Raman Chopra, +9

Proceedings of the National Academy of Sciences

Histone ModificationsEpigenetic ChangeGeneticsMolecular BiologyNeurochemical Biomarkers +19

Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson’s disease

Joseph J. Locascio, Shirley Eberly, Zhixiang Liao, +25

Brain

FGF18 Represses Noggin Expression and Is Induced by Calcineurin

Martina I. Reinhold, Makoto Abe, Ravi M. Kapadia, +2

Journal of Biological Chemistry

Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease

Xianjun Dong, Yunfei Bai, Zhixiang Liao, +9

Nature Communications