Sheila Heitner

Intratumoral Spread of Wild-Type Adenovirus Is Limited After Local Injection of Human Xenograft Tumors: Virus Persists and Spreads Systemically at Late Time Points

Harald Sauthoff, Jing Hu, Cielo Maca et al. · Human Gene Therapy · 2003 · 122 citations

Viral Replication, Immunology, Pathology +16

Wild-Type Adenovirus Decreases Tumor Xenograft Growth, but Despite Viral Persistence Complete Tumor Responses Are Rarely Achieved—Deletion of the Viral E1b-19-kD Gene Increases the Viral Oncolytic Effect

Denise Harrison, Harald Sauthoff, Sheila Heitner et al. · Human Gene Therapy · 2001 · 100 citations

Viral Replication, Synthetic Virology, Immunology +17

Deletion of the Adenoviral E1b-19kD Gene Enhances Tumor Cell Killing of a Replicating Adenoviral Vector

Harald Sauthoff, Sheila Heitner, William N. Rom et al. · Human Gene Therapy · 2000 · 94 citations

Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression

Teona Pipiya, Harald Sauthoff, Yunxia Huang et al. · Gene Therapy · 2005 · 86 citations

Tumor Biology, Redox Regulator, Viral Protein Expression +11

Targeting the Replication of Adenoviral Gene Therapy Vectors to Lung Cancer Cells: The Importance of the Adenoviral E1b-55kD Gene

John G. Hay, N Shapiro, Harald Sauthoff et al. · Human Gene Therapy · 1999 · 71 citations

Tumor Biology, Viral Replication, Systems Biology +15