Scott B. Vafai

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang et al. · Cell · 2008 · 2K citations · Full text

Mitochondrial Function, Medicine, Natural Sciences +6

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

Xiaoyan Bao, Shao‐En Ong, Olga Goldberger et al. · eLife · 2016 · 448 citations · Full text

Reductive Stress, Systems Biology, Mitochondrial Function +14

Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting <i>PCSK9</i> in Nonhuman Primate and Mouse Models

Richard Lee, Anne Marie Mazzola, Maurine Braun et al. · Circulation · 2022 · 186 citations

PGC1α Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis

Kavita Bhalla, Bor Jang Hwang, Ruby E. Dewi et al. · Cancer Research · 2011 · 184 citations · Full text

Metabolic Remodeling, Cancer Biology, Pgc1α Expression +19

A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering

Tsz‐Leung To, Alejandro M. Cuadros, Hardik Shah et al. · Cell · 2019 · 151 citations · Full text

Mitochondrial Disease, Mitochondrial Function, Genetics +8