David N. DeHart

Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells

Eduardo N. Maldonado, Kely L. Sheldon, David N. DeHart et al. · Journal of Biological Chemistry · 2013 · 257 citations · Full text

Life Sciences, Cell Biology, Oncology +12

Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells

David N. DeHart, Diana Fang, Kareem A. Heslop et al. · Biochemical Pharmacology · 2017 · 211 citations · Full text

Life Sciences, Cell Biology, Oncology +17

JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells

Kareem A. Heslop, Amandine Rovini, Elizabeth G. Hunt et al. · Biochemical Pharmacology · 2019 · 89 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells

David N. DeHart, John J. Lemasters, Eduardo N. Maldonado · SLAS DISCOVERY · 2017 · 42 citations · Full text

Life Sciences, Oncology, Pharmacology +15