Charles Redwood

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

Christopher N. Toepfer, Amanda C. Garfinkel, Gabriela Venturini et al. · Circulation · 2020 · 326 citations · Full text

Life Sciences, Cardiology, Molecular Biology +16

Evidence From Human Myectomy Samples That <i>MYBPC3</i> Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency

Steven B. Marston, O’Neal Copeland, Adam Jacques et al. · Circulation Research · 2009 · 240 citations · Full text

Medicine, Cardiology, Genetics +13

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

Jens Mogensen, Ross T. Murphy, Tony Shaw et al. · Journal of the American College of Cardiology · 2004 · 232 citations

Medicine, Cardiology, Genetics +10

Hypertrophic cardiomyopathy mutations in <i>MYBPC3</i> dysregulate myosin

Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel et al. · Science Translational Medicine · 2019 · 214 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Dilated and Hypertrophic Cardiomyopathy Mutations in Troponin and α-Tropomyosin Have Opposing Effects on the Calcium Affinity of Cardiac Thin Filaments

Paul Robinson, Peter Griffiths, Hugh Watkins et al. · Circulation Research · 2007 · 211 citations · Full text

Life Sciences, Biochemistry, Cardiology +17