Hiroyuki Moritomo

Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110α inhibitors

Masahiko Hayakawa, Hiroyuki Kaizawa, Hiroyuki Moritomo et al. · Bioorganic & Medicinal Chemistry · 2006 · 193 citations

Molecular Pharmacology, Medicinal Chemistry, Derivatives +12

Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors

Masahiko Hayakawa, Hiroyuki Kaizawa, Hiroyuki Moritomo et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 137 citations · Full text

Biochemistry, Medicine, Natural Sciences +6

Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2

Ikumi Kuriwaki, Minoru Kameda, Hiroyuki Hisamichi et al. · Bioorganic & Medicinal Chemistry · 2020 · 36 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Medicine +14

Construction of three types of fused isoindoles via furan-pyrrole ring exchange reaction

Mase Lee, Hiroyuki Moritomo, Ken Kanematsu · Tetrahedron · 1996 · 17 citations

Materials Science, Exchange Reaction, Engineering +5

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors

S. Nagashima, Hiroshi Nagata, Masahiro Iwata et al. · Bioorganic & Medicinal Chemistry · 2008 · 15 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +9