Hiroyasu Takemoto

Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles

Hyun Jin Kim, Hiroyasu Takemoto, Yu Yi et al. · ACS Nano · 2014 · 137 citations

Nanoparticles, Nanotherapeutics, Engineering +24

Poly(vinyl alcohol) boosting therapeutic potential of <i>p</i> -boronophenylalanine in neutron capture therapy by modulating metabolism

Takahiro Nomoto, Yukiya Inoue, Ying Yao et al. · Science Advances · 2020 · 131 citations · Full text

Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system

Hiroyasu Takemoto, Atsushi Ishii, Kanjiro Miyata et al. · Biomaterials · 2010 · 123 citations

Engineering, Polymer-drug Conjugate, Drug Delivery Systems +8

Acidic pH‐Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFNα‐Associated Immune Response

Hiroyasu Takemoto, Kanjiro Miyata, Shota Hattori et al. · Angewandte Chemie International Edition · 2013 · 117 citations

Sirna Conjugate, Innate Immune System, Immunology +18

Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles

Frederico Pittella, Horacio Cabral, Yoshinori Maeda et al. · Journal of Controlled Release · 2014 · 116 citations

Nanomedicine, Engineering, Pancreatic Cancer +11