Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons

Yasushi Hojo, Takaaki Hattori, Taihei Enami, +10

Proceedings of the National Academy of Sciences

Cytochromes P45017αSocial SciencesOxidative StressMolecular PharmacologyNeuroendocrine Mechanism +17

Neurosteroid Synthesis by Cytochrome P450-Containing Systems Localized in the Rat Brain Hippocampal Neurons: N-Methyl-d-Aspartate and Calcium-Dependent Synthesis

Tetsuya Kimoto, Tomokazu Tsurugizawa, Y. Ohta, +5

Endocrinology

Calcium-dependent SynthesisNeurotransmitterGlutamate ReceptorsNeurosteroid SynthesisRedox Partners +15

Rapid modulation of long‐term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons

Hideo Mukai, Tomokazu Tsurugizawa, Gen Murakami, +17

Journal of Neurochemistry

Female hippocampal estrogens have a significant correlation with cyclic fluctuation of hippocampal spines

Asami Kato, Yasushi Hojo, Shimpei Higo, +5

Frontiers in Neural Circuits

Female Hippocampal EstrogensCyclic FluctuationNeuroendocrinologyGynecologyFemale Reproductive Function +19

Comparison between Hippocampus-Synthesized and Circulation-Derived Sex Steroids in the Hippocampus

Yasushi Hojo, Shimpei Higo, Hirotaka Ishii, +8

Endocrinology

Mild exercise increases dihydrotestosterone in hippocampus providing evidence for androgenic mediation of neurogenesis

Masahiro Okamoto, Yasushi Hojo, Koshiro Inoue, +4

Proceedings of the National Academy of Sciences

Estradiol rapidly modulates synaptic plasticity of hippocampal neurons: Involvement of kinase networks

Yoshitaka Hasegawa, Yasushi Hojo, Hiroki Kojima, +8

Brain Research

Synaptic PlasticitySynaptic SignalingNeurophysiologyHormonal ReceptorHippocampal Neurons +9

Rapid increase of spines by dihydrotestosterone and testosterone in hippocampal neurons: Dependence on synaptic androgen receptor and kinase networks

Yusuke Hatanaka, Yasushi Hojo, Hideo Mukai, +7

Brain Research

Synaptic PlasticityNeuroanatomySynaptic TransmissionPhysiologyHormonal Receptor +7

Hippocampal Synthesis of Sex Steroids and Corticosteroids: Essential for Modulation of Synaptic Plasticity

Yasushi Hojo, Shimpei Higo, Suguru Kawato, +8

Frontiers in Endocrinology

Comparison between basal and apical dendritic spines in estrogen-induced rapid spinogenesis of CA1 principal neurons in the adult hippocampus

Gen Murakami, Tomokazu Tsurugizawa, Yusuke Hatanaka, +8

Biochemical and Biophysical Research Communications

Adult HippocampusSynaptic PlasticityMolecular NeuroscienceCa1 Principal NeuronsNeurophysiology +12