Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment

Shuai Guo, Kun Li, Bo Hu, +11

Exploration

NanoparticlesEngineeringGene DeliveryBiomedical EngineeringNanomedicine +14

Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia

Bo Hu, Bo Li, Kun Li, +14

Science Advances

Fluorinated Oligoethylenimine Nanoassemblies for Efficient siRNA-Mediated Gene Silencing in Serum-Containing Media by Effective Endosomal Escape

Tingbin Zhang, Yuanyu Huang, Xiaowei Ma, +13

Nano Letters

Ionizable lipid-assisted efficient hepatic delivery of gene editing elements for oncotherapy

Chunhui Li, Tongren Yang, Yuhua Weng, +8

Bioactive Materials

siRNA Knockdown of RRM2 Effectively Suppressed Pancreatic Tumor Growth Alone or Synergistically with Doxorubicin

Shuquan Zheng, Xiaoxia Wang, Yuhua Weng, +13

Molecular Therapy — Nucleic Acids

ROS-Activatable siRNA-Engineered Polyplex for NIR-Triggered Synergistic Cancer Treatment

Yuhua Weng, Ziyang Cao, Shuai Guo, +7

ACS Applied Materials & Interfaces

Small interfering RNA targeting IKKβ prevents renal ischemia-reperfusion injury in rats

Xin Wan, Li Fan, Bo Hu, +4

American Journal of Physiology-Renal Physiology

Acute Lung InjuryRenal PathologyImmunologyRenal InflammationCell Death +21

Hydrothermal Syntheses and Structural Characterizations of Polyoxometalate (Mo/W) Compounds Consisting of M-L Cations, (M = Mn, Co, Ni, Cu, Zn; L = 3-(2-Pyridyl)pyrazole)

Xiutang Zhang, Peihai Wei, Daofeng Sun, +5

Crystal Growth & Design

Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma

Shaoping Jiang, Wenpei Li, Jun Yang, +8

ACS Nano

Targeted reprogramming of tumor-associated macrophages for overcoming glioblastoma resistance to chemotherapy and immunotherapy

Jianan Li, Jun Yang, Shaoping Jiang, +9

Biomaterials

Neuro-oncologyTumor-associated MacrophagesCancer ImmunosurveillanceImmunologyTumor Immunity +10