Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Michael R. Johnson, Jacques Behmoaras, Leonardo Bottolo, +39

Nature Communications

Localized delivery of fibroblast growth factor–2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

Beatrice Paradiso, Peggy Marconi, Silvia Zucchini, +15

Proceedings of the National Academy of Sciences

Temporal Lobe OriginNeuromodulation TherapiesSocial SciencesNeuroinflammationFibroblast Growth Factor–2 +14

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

Michael R. Johnson, Kirill Shkura, Sarah R. Langley, +31

Nature Neuroscience

Neurodevelopmental DisordersBrain StructureDevelopmental Cognitive NeuroscienceMedicineGenetics +12

Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy

Manuela Mazzuferi, Gaurav Kumar, Jonathan van Eyll, +3

Annals of Neurology

Rapid epileptogenesis in the mouse pilocarpine model: Video-EEG, pharmacokinetic and histopathological characterization

Manuela Mazzuferi, Gaurav Kumar, Chiara Rospo, +1

Experimental Neurology

Rapid EpileptogenesisNeurophysiologyNeuroanatomyMedicineHistopathological Characterization +11

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target

Prashant K. Srivastava, Jonathan van Eyll, Patrice Godard, +23

Nature Communications

Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery

Andrée Delahaye‐Duriez, Prashant K. Srivastava, Kirill Shkura, +12

Genome biology

Genome-wide analysis of differential RNA editing in epilepsy

Prashant K. Srivastava, Marta Bagnati, Andrée Delahaye‐Duriez, +12

Genome Research

Generalized EpilepsyDifferential Rna EditingGeneticsLong Non-coding RnaGene Editing +8

Expression pattern of synaptic vesicle protein 2 (<scp>SV</scp>2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis

Julie Crèvecœur, R. M. Kaminski, Bernard Rogister, +12

Neuropathology and Applied Neurobiology

GABA _A -current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA _A “phasic” receptors

Eleonora Palma, Cristina Roseti, Francesca Maiolino, +10

Proceedings of the National Academy of Sciences

NeuropsychologyBrain MechanismSynaptic TransmissionNeurotransmitterTemporal Lobe Epilepsy +22