Concepedia

Sean Shadle

SS

Statistics

Publications

10

Citations

859

H-Index

10

Active since

2011

Affiliations

Fred Hutch Cancer Center(Current)

Leiden University Medical Center

University of Washington

University of Utah

University of Rochester Medical Center

Sean Shadle is an author at Fred Hutch Cancer Center specializing in medicine, cell biology, and developmental biology.

Top concepts

Publications per year

2011–2021

10

Publications

10

KDM5B regulates embryonic stem cell self‐renewal and represses cryptic intragenic transcription

Liangqi Xie, Carl Pelz, Wensi Wang et al. · The EMBO Journal · 2011 · 173 citations · Full text

DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade

Guo-Liang Chew, Amy E. Campbell, Emma De Neef et al. · Developmental Cell · 2019 · 120 citations · Full text

, , +6

Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells

Sujatha Jagannathan, Sean Shadle, Rebecca Resnick et al. · Human Molecular Genetics · 2016 · 115 citations

p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models

Edward J. Grow, B. D. Weaver, Christina M. Smith et al. · Nature Genetics · 2021 · 109 citations · Full text

, , +9

DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

Sean Shadle, Jun Zhong, Amy E. Campbell et al. · PLoS Genetics · 2017 · 95 citations · Full text

, , +15

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