Extracellular histones are clinically relevant mediators in the pathogenesis of acute respiratory distress syndrome

Xin Lv, Tao Wen, Jiong Song, +5

Respiratory Research

Extracellular Histones Play an Inflammatory Role in Acid Aspiration-induced Acute Respiratory Distress Syndrome

Yanlin Zhang, Zongmei Wen, Li Guan, +5

Anesthesiology

Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

Zongmei Wen, Zhen Lei, Yao Lu, +7

Cell Death and Disease

Sulfated polysaccharides and immune response: promoter or inhibitor?

Dongwei Chen, Xudong Wu, Zongmei Wen

PubMed

ImmunologyGlycobiologyInnate ImmunityImmune SystemImmunotherapy +14

Neutrophils Counteract Autophagy-Mediated Anti-Inflammatory Mechanisms in Alveolar Macrophage: Role in Posthemorrhagic Shock Acute Lung Inflammation

Zongmei Wen, Liyan Fan, Yuehua Li, +8

The Journal of Immunology

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyRenal Inflammation +16

Exploratory investigation of plasma metabolomics in human lung adenocarcinoma

Tao Wen, Liang Gao, Zongmei Wen, +4

Molecular BioSystems

BiochemistryPlasma MetabolomicsMedicinePharmacologyMetabolomic Profiling +12

Circulating histones exacerbate inflammation in mice with acute liver failure

Zongmei Wen, Yan Liu, Feng Li, +4

Journal of Cellular Biochemistry

Liver FibrosisLipid PeroxidationImmunologyCell DeathPathology +19

Hemorrhagic Shock Augments Nlrp3 Inflammasome Activation in the Lung through Impaired Pyrin Induction

Peng Xu, Zongmei Wen, Xueyin Shi, +10

The Journal of Immunology

Acute Lung InjuryIl-10 ExpressionInflammatory Lung DiseaseLung InflammationImmunology +26

Metabolic Profiling of Plasma from Benign and Malignant Pulmonary Nodules Patients Using Mass Spectrometry-Based Metabolomics

Liang Gao, Zongmei Wen, Chunyan Wu, +2

Metabolites

Metabolomic ProfilingPathologyBenign SpnsSolitary Pulmonary NoduleMalignant Spns +17

Extracellular histones aggravate inflammation in ARDS by promoting alveolar macrophage pyroptosis

Ping Jiang, Jin Yang, Meng Sun, +4

Molecular Immunology

InflammationMitophagyExtracellular HistonesAlveolar Macrophage PyroptosisAutoimmune Disease +10