Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

Huaimin Wang, Zhaoqianqi Feng, Youzhi Wang, +3

Journal of the American Chemical Society

Bioorganic ChemistryAcquired Drug ResistanceChemical BiologyRedox BiologyTumor Biology +17

Enzymatic Assemblies Disrupt the Membrane and Target Endoplasmic Reticulum for Selective Cancer Cell Death

Zhaoqianqi Feng, Huaimin Wang, Shiyu Wang, +4

Journal of the American Chemical Society

Proteinlipid InteractionApoptosisCell DeathLipid MovementLipid Transfer +17

Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors

Zhaoqianqi Feng, Xiuguo Han, Huaimin Wang, +2

Chem

BiochemistryNatural SciencesPeptide EngineeringPeptide LibraryProtein Engineering +2

Enzyme-Instructed Assembly and Disassembly Processes for Targeting Downregulation in Cancer Cells

Zhaoqianqi Feng, Huaimin Wang, Rong Zhou, +2

Journal of the American Chemical Society

Protein AssemblyMolecular BiologyChemical BiologyTumor BiologyProtein Folding +18

Self-Assembling Ability Determines the Activity of Enzyme-Instructed Self-Assembly for Inhibiting Cancer Cells

Zhaoqianqi Feng, Huaimin Wang, Xiaoyi Chen, +1

Journal of the American Chemical Society

Protein AssemblyPeptide EngineeringMolecular BiologyCytoskeletonBiological Computing +18

Active Probes for Imaging Membrane Dynamics of Live Cells with High Spatial and Temporal Resolution over Extended Time Scales and Areas

Huaimin Wang, Zhaoqianqi Feng, Steven J. Del Signore, +2

Journal of the American Chemical Society

Proteinlipid InteractionEngineeringMicroscopyBiomedical EngineeringLipid Movement +22

Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells

Huaimin Wang, Zhaoqianqi Feng, Dongdong Wu, +6

Journal of the American Chemical Society

Intercellular Instructed-Assembly Mimics Protein Dynamics To Induce Cell Spheroids

Huaimin Wang, Zhaoqianqi Feng, Bing Xu

Journal of the American Chemical Society

Instructed Assembly of Peptides for Intracellular Enzyme Sequestration

Zhaoqianqi Feng, Huaimin Wang, Bing Xu

Journal of the American Chemical Society

Proteinlipid InteractionProtein AssemblyPeptide EngineeringChemical BiologyProtein Folding +16

Nucleopeptide Assemblies Selectively Sequester ATP in Cancer Cells to Increase the Efficacy of Doxorubicin

Huaimin Wang, Zhaoqianqi Feng, Yanan Qin, +2

Angewandte Chemie International Edition

More NucleopeptidesChemical BiologyCancer BiologyOncologyCancer Cell Biology +16