Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

Yuto Unoh, Shota Uehara, Kenji Nakahara, +22

Journal of Medicinal Chemistry

Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice

Yukiko Fujisawa, Teruhisa Kato, S. Ohki, +5

Proceedings of the National Academy of Sciences

Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis

Shigeyuki Kitamura, Teruhisa Kato, Mitsuru Iida, +7

Life Sciences

BiochemistryMedicinePhysiologyAnti-thyroid Hormonal ActivityThyroid Disease +6

Salivary bisphenol-A levels detected by ELISA after restoration with composite resin

Noriko Sasaki, Katsuhiro Okuda, Teruhisa Kato, +6

Journal of Materials Science Materials in Medicine

Salivary Bisphenol-a LevelsBioanalysisOral BiologyAnalytical ChemistryComposite Resin +3

S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters

Michihito Sasaki, Koshiro Tabata, Mai Kishimoto, +19

Science Translational Medicine

High throughput solubility measurement with automated polarized light microscopy analysis

Kiyohiko Sugano, Teruhisa Kato, Kentaro Suzuki, +3

Journal of Pharmaceutical Sciences

EngineeringMicroscopyOptical PropertiesMicroscopy MethodApplied Physics +7

Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

Yuto Unoh, Shota Uehara, Kenji Nakahara, +22

Coronavirus Disease 2019Molecular PharmacologyMedicinal ChemistryVirtual ScreeningMedicine +13

Epitaxial growth and optical investigations of ZnTeO alloys

Yu Nabetani, T. Okuno, Kagari Aoki, +3

physica status solidi (a)

Optical MaterialsEngineeringCrystal Growth TechnologySemiconductor NanostructuresSemiconductors +14

Estrogenic and Anti-Androgenic Activities of Benzophenones in Human Estrogen and Androgen Receptor Mediated Mammalian Reporter Gene Assays

Yoko KAWAMURA, Motoh Mutsuga, Teruhisa Kato, +2

JOURNAL OF HEALTH SCIENCE

Reporter GeneFemale Reproductive FunctionReproductive EndocrinologyMolecular PharmacologySteroid Metabolism +17

Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel

Thomas Ryckmans, Aisah A. Aubdool, Jennifer V. Bodkin, +12

Bioorganic & Medicinal Chemistry Letters

Trpa1 ChannelMolecular PhysiologySignal TransductionBiochemistryFunctional Selectivity +9