Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans

Eric V. Granowitz, Reuven Porat, James W. Mier, +6

Cytokine

InflammationCytokineImmunomodulatory EffectsAutoimmune DiseaseImmunotoxicology +8

Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism

G. Kaplanski, Catherine Farnarier, S. Kaplanski, +4

Blood

Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans.

Eric V. Granowitz, Reuven Porat, J W Mier, +7

The Journal of Immunology

InflammationCytokineEndotoxin ToleranceAllergyIntravenous Endotoxin +10

Enhancement of Growth of Virulent Strains of <i>Escherichia coli</i> by Interleukin-1

Reuven Porat, Burton D. Clark, Sheldon Wolff, +1

Science

Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event

Gilles Kaplanski, Reuven Porat, K Aiura, +3

Blood

Interleukin‐1 (IL‐1) receptor blockade reduces endotoxin and <i>Borrelia burgdorferi</i> ‐stimulated IL‐8 synthesis in human mononuclear cells

Reuven Porat, Debra D. Poutsiaka, Laurie C. Miller, +2

The FASEB Journal

Hematologic and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans

EV Granowitz, Reuven Porat, J W Mier, +7

Blood

Hematologic and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans

EV Granowitz, Reuven Porat, J W Mier, +7

Blood

Clinical and inflammatory effects of dietary l-arginine in patients with intractable angina pectoris

Arnon Blum, Reuven Porat, Uri Rosenschein, +4

The American Journal of Cardiology

InflammationDietary L-arginineCardiovascular DiseaseVascular PharmacologyPharmacology +5

Selective pressures and lipopolysaccharide subunits as determinants of resistance of clinical isolates of gram-negative bacilli to human serum

Reuven Porat, Margaret A. Johns, William R. McCabe

Infection and Immunity

Selective PressuresNormal Human SerumGram-negative BacteriologyAntimicrobial SusceptibilityHealth Sciences +12