Chandrashekhara Manithody

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Jong‐Sup Bae, Likui Yang, Chandrashekhara Manithody et al. · Blood · 2007 · 222 citations · Full text

Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor

Peyman Dinarvand, Seyed Mahdi Hassanian, Shabir H. Qureshi et al. · Blood · 2013 · 117 citations · Full text

Engineering a Disulfide Bond to Stabilize the Calcium-binding Loop of Activated Protein C Eliminates Its Anticoagulant but Not Its Protective Signaling Properties

Jong‐Sup Bae, Likui Yang, Chandrashekhara Manithody et al. · Journal of Biological Chemistry · 2007 · 102 citations · Full text

Protein Assembly, Immunology, Molecular Biology +27

Identification of a Specific Exosite on Activated Protein C for Interaction with Protease-activated Receptor 1

Likui Yang, Jong‐Sup Bae, Chandrashekhara Manithody et al. · Journal of Biological Chemistry · 2007 · 61 citations · Full text

Protein Secretion, Immunology, Molecular Biology +19

Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury

Yina Ma, Jinli Wang, Junjie Gao et al. · Thrombosis and Haemostasis · 2014 · 61 citations · Full text

Cardiac Muscle, Heart Failure, Ampk Activity +20