Immune Cell–Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation

Tobias Bald, Jennifer Landsberg, Dorys Lopez-Ramos, +11

Cancer Discovery

Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma.

Julia Steitz, Jürgen Brück, Jack Lenz, +2

PubMed

ImmunologyImmunologic MechanismT CellsImmunotherapyT-cell-dependent Immune Defense +14

Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: identification of an H2-Kd-restricted CTL epitope

Andrea Gambotto, Grzegorz Dworacki, Vito R. Cicinnati, +5

Gene Therapy

Knockout MouseSignal TransductionImmunologyAntigen ProcessingAutoimmunity +5

Systemic application of CpG‐rich DNA suppresses adaptive T cell immunity via induction of IDO

Gerhard Wingender, Natalio Garbi, Beatrix Schumak, +16

European Journal of Immunology

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Benjamin Theek, Maike Baues, Tarun Ojha, +6

Journal of Controlled Release

Extracellular MicrovesiclesLiposome AccumulationTumor TargetingLow EprRadiation Oncology +4

Genetic immunization of mice with human tyrosinase-related protein 2: Implications for the immunotherapy of melanoma

Julia Steitz, J�rgen Br�ck, Kerstin Steinbrink, +3

International Journal of Cancer

Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4+ T cell-dependent mechanism

Julia Steitz, Jürgen Brück, Jürgen Knop, +1

Gene Therapy

Cellular ImmunityAdenovirus-transduced Dendritic CellsCancer ImmunosurveillanceMelanomaImmunology +8

Absence of CD26 expression on skin-homing CLA+ CD4+ T lymphocytes in peripheral blood is a highly sensitive marker for early diagnosis and therapeutic monitoring of patients with Sezary syndrome

Joerg Wenzel, Evelyn Gaffal, Julia Steitz, +3

Clinical and Experimental Dermatology

ImmunohematologyCd26 ExpressionImmunodeficienciesImmunologyPathology +17

Role of the Chemokine Receptor CCR4 and its Ligand Thymus- and Activation-Regulated Chemokine/CCL17 for Lymphocyte Recruitment in Cutaneous Lupus Erythematosus

Joerg Wenzel, Stephanie Henze, Eva Wörenkämper, +4

Journal of Investigative Dermatology

InflammationLigand Thymus-Chemokine BiologyAutoimmune DiseaseLupus +8

Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity

Thomas Tüting, Julia Steitz, Jürgen Brück, +6

The Journal of Gene Medicine