Leonardo Bontempi

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

Marco Peviani, Eleonora Salvaneschi, Leonardo Bontempi et al. · Neurobiology of Disease · 2013 · 124 citations · Full text

Sigma-1 Receptor, Amyotrophic Lateral Sclerosis, Motor Neuron Disease +8

Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice

Marco Pignatelli, Hugo A. Tejeda, David J. Barker et al. · Molecular Psychiatry · 2020 · 60 citations · Full text

Dopamine D3 and acetylcholine nicotinic receptor heteromerization in midbrain dopamine neurons: Relevance for neuroplasticity

Leonardo Bontempi, Paola Savoia, Federica Bono et al. · European Neuropsychopharmacology · 2017 · 36 citations

Neuroanatomy, Physiology, Midbrain Dopamine Neurons +10

Striatal Astrocytes Shape Behavioral Flexibility via Regulation of the Glutamate Transporter EAAT2

Arjen J. Boender, Leonardo Bontempi, Luca Nava et al. · Biological Psychiatry · 2020 · 22 citations · Full text

Synaptic Plasticity, Neurophysiology, Neuroanatomy +9

The novel hybrid agonist HyNDA-1 targets the D3R-nAChR heteromeric complex in dopaminergic neurons

Carlo Matera, Federica Bono, Silvia Pelucchi et al. · Biochemical Pharmacology · 2019 · 18 citations · Full text

Dopaminergic Neurons, Medicine, Functional Selectivity +9