Shaikh Abdul Rajjak

Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Sunil Kumar Singh, P. Ganapati Reddy, K. Srinivasa Rao et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 138 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis and SAR/3D-QSAR studies on the COX-2 inhibitory activity of 1,5-diarylpyrazoles to validate the modified pharmacophore

Sunil Kumar Singh, V. Saibaba, K. Srinivasa Rao et al. · European Journal of Medicinal Chemistry · 2005 · 40 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors

Sunil Kumar Singh, Saibaba Vobbalareddy, S. Shivaramakrishna et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 31 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +10

3D-QSAR CoMFA, CoMSIA studies on substituted ureas as Raf-1 kinase inhibitors and its confirmation with structure-based studies

Ram Thaimattam, Pankaj Daga, Shaikh Abdul Rajjak et al. · Bioorganic & Medicinal Chemistry · 2004 · 24 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

2-Hydroxymethyl-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide (DRF-4367): an orally active COX-2 inhibitor identified through pharmacophoric modulation

Sunil Kumar Singh, Saibaba Vobbalareddy, Srinivasa Rao Kalleda et al. · Organic & Biomolecular Chemistry · 2004 · 13 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14