PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

Simona Frateschi, Eric Camerer, Giovanna Crisante, +14

Nature Communications

Altered Cap1/prss8 ExpressionImmunologyImmune RegulationSkin DisordersDermatology +22

ENaC‐mediated alveolar fluid clearance and lung fluid balance depend on the channel‐activating protease 1

Carole Planès, Nadia Randrianarison, Roch‐Philippe Charles, +7

EMBO Molecular Medicine

Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype

Jérémie Canonica, Chloé Sergi, Marc Maillard, +8

Pflügers Archiv - European Journal of Physiology

GlomerulonephritisUrologyRenal FunctionMedicinePhysiology +8

Severe Salt–Losing Syndrome and Hyperkalemia Induced by Adult Nephron–Specific Knockout of the Epithelial Sodium Channel α-Subunit

Romain Perrier, Emilie Boscardin, Sumedha Malsure, +9

Journal of the American Society of Nephrology

Mutations of the Serine Protease CAP1/Prss8 Lead to Reduced Embryonic Viability, Skin Defects, and Decreased ENaC Activity

Simona Frateschi, Anna Keppner, Sumedha Malsure, +7

American Journal Of Pathology

Skin DevelopmentDevelopmental BiologySkin DefectsEnac ActivityCutaneous Biology +5

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Edith Hümmler, Aline Dousse, Audrey Rieder, +6

PLoS ONE

Skin DevelopmentDevelopmental BiologySerine Protease Cap1/prss8Placental DevelopmentPathology +10

The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin‐1 (PN‐1) inhibition

Giovanna Crisante, Laura Battista, Justyna Iwaszkiewicz, +6

The FASEB Journal

ImmunologyMolecular BiologySerine ProteasesDermatologySerine Protease Inhibitors +15

Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl– Cotransporter NCC and Transiently Affects Sodium Handling

Jérémie Canonica, Simona Frateschi, Emilie Boscardin, +13

Frontiers in Physiology

Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway

Elodie Ehret, Yannick Jäger, Chloé Sergi, +13

International Journal of Molecular Sciences