Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis

Deepak Kaushal, Taylor W. Foreman, Uma Shankar Gautam, +16

Nature Communications

VaccinationVaccinologyMtb MutantMucosal VaccinationPulmonary Tuberculosis +12

In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of<i>Mycobacterium tuberculosis</i>

Uma Shankar Gautam, Taylor W. Foreman, Allison N. Bucşan, +16

Proceedings of the National Academy of Sciences

The DosR Regulon Modulates Adaptive Immunity and Is Essential for <i>Mycobacterium tuberculosis</i> Persistence

Smriti Mehra, Taylor W. Foreman, Peter J. Didier, +16

American Journal of Respiratory and Critical Care Medicine

Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of <i>Mycobacterium tuberculosis</i>

Teresa A. Hudock, Taylor W. Foreman, Nirmalya Bandyopadhyay, +14

American Journal of Respiratory Cell and Molecular Biology

DosS Is Required for the Complete Virulence of <i>Mycobacterium tuberculosis</i> in Mice with Classical Granulomatous Lesions

Uma Shankar Gautam, Amanda McGillivray, Smriti Mehra, +9

American Journal of Respiratory Cell and Molecular Biology

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationImmunologyImmune Regulation +21

Essentiality of DevR/DosR Interaction with SigA for the Dormancy Survival Program in Mycobacterium tuberculosis

Uma Shankar Gautam, Kriti Sikri, Atul Vashist, +2

Journal of Bacteriology

Role of TNF in the Altered Interaction of Dormant Mycobacterium tuberculosis with Host Macrophages

Uma Shankar Gautam, Smriti Mehra, Muhammad Ahsan, +3

PLoS ONE

Innate Immune SystemImmunologyMtb ReplicationHost MacrophagesInnate Immunity +16

The Mycobacterium tuberculosis Rv2745c Plays an Important Role in Responding to Redox Stress

Amanda McGillivray, Nadia Golden, Uma Shankar Gautam, +2

PLoS ONE

Molecular RegulationMolecular BiologyInnate ImmunityRedox BiologyOxidative Stress +23

Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner

Uma Shankar Gautam, Smriti Mehra, Priyanka Kumari, +4

Communications Biology

In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice

Uma Shankar Gautam, Smriti Mehra, Deepak Kaushal

PLoS ONE

Microbial PathogensInnate Immune SystemImmune RegulationImmunologyMolecular Biology +20