K A Moffatt

Stable expression of the nuclear vitamin D receptor in the human prostatic carcinoma cell line JCA-1: evidence that the antiproliferative effects of 1 alpha, 25-dihydroxyvitamin D3 are mediated exclusively through the genomic signaling pathway.

Tammy E. Hedlund, K A Moffatt, Gary J. Miller · Endocrinology · 1996 · 116 citations · Full text

Urology, Nuclear Vdr, Chemoprevention Strategy +14

1Alpha,25dihydroxyvitamin D3 and platinum drugs act synergistically to inhibit the growth of prostate cancer cell lines.

K A Moffatt, W U Johannes, Gary J. Miller · PubMed · 1999 · 107 citations

Urology, Chemoprevention Strategy, Medicine +12

Vitamin D receptor expression is required for growth modulation by 1α,25-dihydroxyvitamin D3 in the human prostatic carcinoma cell line ALVA-31

Tammy E. Hedlund, K A Moffatt, Gary J. Miller · The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 88 citations

Tumor Biology, Urology, Growth Modulation +5

Growth inhibitory effects of 1alpha, 25-dihydroxyvitamin D(3) are mediated by increased levels of p21 in the prostatic carcinoma cell line ALVA-31.

K A Moffatt, W U Johannes, Tammy E. Hedlund et al. · PubMed · 2001 · 70 citations

Chemoprevention Strategy, Tumor Biology, Oncology +16

Three synthetic vitamin D analogues induce prostate-specific acid phosphatase and prostate-specific antigen while inhibiting the growth of human prostate cancer cells in a vitamin D receptor-dependent fashion.

Tammy E. Hedlund, K A Moffatt, Milan R. Uskoković et al. · PubMed · 1997 · 47 citations

Urology, Such Analogues, Chemoprevention Strategy +13