Efficacy of third-party chimeric antigen receptor modified peripheral blood natural killer cells for adoptive cell therapy of B-cell precursor acute lymphoblastic leukemia

Concetta Quintarelli, Simona Sivori, Simona Caruso, +21

Leukemia

Hematological MalignancyCell TherapyMalignant Blood DisorderHematologyImmunology +8

Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma

Domenico Orlando, Evelina Miele, Biagio De Angelis, +17

Cancer Research

CD28.OX40 co-stimulatory combination is associated with long in vivo persistence and high activity of CAR.CD30 T-cells

Marika Guercio, Domenico Orlando, Stefano Di Cecca, +27

Haematologica

Adaptive Immune SystemT-regulatory CellImmunologyImmunologic MechanismCd4 T Cell Responses +19

Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies

Marika Guercio, Simona Manni, Iolanda Boffa, +16

Frontiers in Immunology

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling

Francesca Nazio, Agnese Pò, Luana Abballe, +28

Acta Neuropathologica

GD2-Targeting CAR T-cell Therapy for Patients with GD2+ Medulloblastoma

Roselia Ciccone, Concetta Quintarelli, Antonio Camera, +28

Clinical Cancer Research

Diabetic microangiopathy: physiopathological, clinical and therapeutic aspects.

Antonio Camera, Eugenia Hopps, Gregorio Caimi

PubMed

PathologyDiabetic MicroangiopathyOxidative StressDiabetic RetinopathyDiabetic Neuropathy +16

GD2 redirected CAR T and activated NK-cell-mediated secretion of IFNγ overcomes MYCN-dependent IDO1 inhibition, contributing to neuroblastoma cell immune escape

Matteo Caforio, Cristina Sorino, Ignazio Caruana, +13

Journal for ImmunoTherapy of Cancer

ImmunologyImmune RegulationImmunoeditingImmunologic MechanismMycn-dependent Ido1 Inhibition +20

Characterization of two novel cell lines, DERL-2 (CD56+/CD3+/TCRγδ+) and DERL-7 (CD56+/CD3−/TCRγδ−), derived from a single patient with CD56+ non-Hodgkin's lymphoma

Rosa Di Noto, Fabrizio Pane, Antonio Camera, +12

Leukemia

Lymphoid NeoplasiaCd56+ Non-hodgkinImmunodeficienciesImmunologyTumor Immunity +9

[Metabolic syndrome: from insulin resistance to adipose tissue dysfunction].

Antonio Camera, Eugenia Hopps, Gregorio Caimi

PubMed

Metabolic DisorderPathologyInsulin SignalingObesityMetabolic Syndrome +14