Response of MAPK pathway to iron oxide nanoparticles in vitro treatment promotes osteogenic differentiation of hBMSCs

Qiwei Wang, Bo Chen, Meng Cao, +8

Biomaterials

Regenerative MedicineTissue EngineeringOxide NanoparticlesEngineeringBone Morphogenic Protein +9

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum

Jiqin Lian, Xiong-Zhi Wu, Fengtian He, +6

Cell Death and Differentiation

Cell AutophagyBcl-2–beclin1 InteractionMedicineApoptosisAutophagy +9

Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

Yang Meng, Wenhua Tang, Yao Dai, +7

Molecular Cancer Therapeutics

Natural Bh3 MimeticMedicinal ChemistryUrologyAntiapoptotic MembersMedicine +13

<b> <i>In vitro</i> </b> Effects of the BH3 Mimetic, (−)-Gossypol, on Head and Neck Squamous Cell Carcinoma Cells

Christopher L. Oliver, Joshua A. Bauer, Keith G. Wolter, +9

Clinical Cancer Research

Molecular Modeling of the Three-Dimensional Structure of Dopamine 3 (D₃) Subtype Receptor:  Discovery of Novel and Potent D₃Ligands through a Hybrid Pharmacophore- and Structure-Based Database Searching Approach

Judith Varady, Xihan Wu, Xueliang Fang, +4

Journal of Medicinal Chemistry

Natural product (−)‐gossypol inhibits colon cancer cell growth by targeting RNA‐binding protein Musashi‐1

Lan Lan, Carl Appelman, Amber R. Smith, +17

Molecular Oncology

Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis

Xiaoqing Wu, Gulhumay Gardashova, Lan Lan, +15

Communications Biology

Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents

Jin Cai, Min Sun, Xiaoqing Wu, +4

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryDerivativesMedicinePotential Anti-tumor Agents +6

NLRP3 inflammasome upregulates PD-L1 expression and contributes to immune suppression in lymphoma

Fei Lu, Yanan Zhao, Yihua Pang, +11

Cancer Letters

ImmunologyPathologyCell DeathImmunologic MechanismImmunotherapy +15

miR-181b increases drug sensitivity in acute myeloid leukemia via targeting HMGB1 and Mcl-1

Fei Lu, Jingru Zhang, Min Ji, +7

International Journal of Oncology