T Fujitsu

Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity.

Nobuo Seki, Yuji Sudo, Tatsunobu Yoshioka et al. · The Journal of Immunology · 1988 · 261 citations

Life Sciences, Immunology, Pathology +14

Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone.

Kenji Iwasaki, Toshifumi Shiraga, Kazuko Nagase et al. · Drug Metabolism and Disposition · 1993 · 106 citations

Life Sciences, Biochemistry, Pharmacology +16

Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.

Kenji Iwasaki, Toshifumi Shiraga, H Matsuda et al. · Drug Metabolism and Disposition · 1995 · 105 citations

Life Sciences, Biochemistry, Pharmacology +17

Interaction of Tacrolimus (FK506) and Its Metabolites with FKBP and Calcineurin

Kouichi Tamura, Tsutomu Fujimura, Kaname IWASAKI et al. · Biochemical and Biophysical Research Communications · 1994 · 61 citations

Pharmacy, Pharmacokinetics, Pharmacology +9

Synthesis and Antiinflammatory and Analgesic Properties of 2-Amino-1H-benzimidazole and 1,2-Dihydro-2-iminocycloheptimidazole Derivatives.

K Taniguchi, Shinji Shigenaga, T Ogahara et al. · Chemical and Pharmaceutical Bulletin · 1993 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9