Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice

Baolin Guo, Jing Chen, Qian Chen, +15

Nature Neuroscience

Neurobiological MechanismNeuropsychologyBehavioral SciencesBehavioral NeuroscienceCortical Remodeling +9

TNF signaling pathway-mediated microglial activation in the PFC underlies acute paradoxical sleep deprivation-induced anxiety-like behaviors in mice

Haiying Liu, Xin Huang, Yaohao Li, +6

Brain Behavior and Immunity

Pfc UnderliesImmunologyAcute PsdNeuroinflammationInflammation +14

Extracellular matrix protein laminin β1 regulates pain sensitivity and anxiodepression-like behaviors in mice

Zhenzhen Li, Wenjuan Han, Zhi‐Chuan Sun, +13

Journal of Clinical Investigation

Pain DisordersPain MedicineSynaptic TransmissionNeuropathic PainMolecular Pain +22

Dissection of the relationship between anxiety and stereotyped self-grooming using the Shank3B mutant autistic model, acute stress model and chronic pain model

Haiying Liu, Xin Huang, Jinwei Xu, +8

Neurobiology of Stress

Psychological Co-morbiditiesAffective NeuroscienceMental HealthPsychologySocial Sciences +22

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

Ming Zhang, Jian Wang, Kaixiang Zhang, +15

Nature Communications

Excitatory and Inhibitory Synaptic Imbalance Caused by Brain-Derived Neurotrophic Factor Deficits During Development in a Valproic Acid Mouse Model of Autism

Chuchu Qi, Andi Chen, Honghui Mao, +7

Frontiers in Molecular Neuroscience

NeuropsychologyDevelopmental Cognitive NeuroscienceVpa ExposureVpa Mouse ModelSocial Sciences +18

CB1R dysfunction of inhibitory synapses in the ACC drives chronic social isolation stress-induced social impairments in male mice

Baolin Guo, Kaiwen Xi, Honghui Mao, +15

Neuron

Social IsolationSynaptic PlasticityCb1r DysfunctionPsychoneuroimmunologyStress Hormone +10

Reversal of hyperactive higher-order thalamus attenuates defensiveness in a mouse model of PTSD

Kaiwen Xi, Haoxiang Xiao, Xin Huang, +12

Science Advances

NeuropsychologyBrain MechanismAffective NeuroscienceSocial SciencesPsychology +16

Translational relevance of behavioral, neural, and electroencephalographic profiles in a mouse model of post-traumatic stress disorder

Kaiwen Xi, Xin Huang, Tiaotiao Liu, +7

Neurobiology of Stress

Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders

Mengmeng Wang, Panpan Xian, Weian Zheng, +11

EMBO Molecular Medicine