Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

Stephen Salloway, Reisa A. Sperling, Nick C. Fox, +21

New England Journal of Medicine

Toll-Like Receptor 8-Mediated Reversal of CD4 ⁺ Regulatory T Cell Function

Guangyong Peng, Zhong Guo, Yukiko Kiniwa, +7

Science

T-regulatory CellImmune RegulationImmunologyRegulatory T CellsCd4+ Regulatory T +21

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis

Jennifer L. McQuade, Carrie R. Daniel, Kenneth R. Hess, +40

The Lancet Oncology

OncologyBody CompositionCancer ManagementMelanomaMetastatic Melanoma +6

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

Myrna R. Rosenfeld, Xiaobu Ye, Jeffrey G. Supko, +17

Autophagy

ImmunologyCell DeathPharmacotherapyHcq 600High-grade Gliomas +21

WormBase 2016: expanding to enable helminth genomic research

Kevin Howe, Bruce J. Bolt, Scott Cain, +31

Nucleic Acids Research

GeneticsWormbase 2016GenomicsSemantic WebBioinformatics Database +18

WormBase: a comprehensive resource for nematode research

Todd Harris, Igor Antoshechkin, Tamberlyn Bieri, +29

Nucleic Acids Research

Nematode ResearchGeneticsGenomicsBioinformatics DatabaseMolecular Ecology +16

Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations

Curtis H. Kugel, Stephen M. Douglass, Marie R. Webster, +40

Clinical Cancer Research

WormBase 2014: new views of curated biology

Todd Harris, Joachim Baran, Tamberlyn Bieri, +30

Nucleic Acids Research

EngineeringGeneticsGenomicsBioinformatics DatabaseHigh Throughput Sequencing +17

A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis

Douglas B. Johnson, Wyatt J. McDonnell, Paula I. González-Ericsson, +30

Nature Medicine

ImmunologyAntiviral ResponsePathologyAutoimmunityT Cell Immunity +6

Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement

Douglas B. Johnson, Mellissa J. Nixon, Yu Wang, +21

JCI Insight

ImmunologyImmunoeditingImmunologic MechanismAntigen ProcessingImmunotherapy +15