Dina Robaa

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Matthias Schiedel, Daniel Herp, Sören Hammelmann et al. · Journal of Medicinal Chemistry · 2017 · 269 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +15

Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from <i>Schistosoma mansoni</i> for the Treatment of Schistosomiasis

Tino Heimburg, Alokta Chakrabarti, Julien Lancelot et al. · Journal of Medicinal Chemistry · 2016 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants

Martin Marek, T.B. Shaik, Tino Heimburg et al. · Journal of Medicinal Chemistry · 2018 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells

Eva Plesch, Cheng‐Chang Chen, Elisabeth Butz et al. · eLife · 2018 · 103 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Katharina Vögerl, Nghia Ong, Johanna Senger et al. · Journal of Medicinal Chemistry · 2019 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17