Frank Cihon

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

Axel Grothey, Eric Van Cutsem, Alberto Sobrero et al. · The Lancet · 2012 · 2.9K citations

Medicine, Oncology, Pharmacology +10

Phase III Study of Carboplatin and Paclitaxel Alone or With Sorafenib in Advanced Non–Small-Cell Lung Cancer

Giorgio V. Scagliotti, Silvia Novello, Joachim von Pawel et al. · Journal of Clinical Oncology · 2010 · 454 citations · Full text

Medicine, Oncology, Pharmacology +17

Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors

Malcolm J. Moore, Holger W. Hirte, Lillian L. Siu et al. · Annals of Oncology · 2005 · 301 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics

Chetan Lathia, John Lettieri, Frank Cihon et al. · Cancer Chemotherapy and Pharmacology · 2005 · 208 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +10

Phase II, Multicenter, Uncontrolled Trial of Single-Agent Sorafenib in Patients With Relapsed or Refractory, Advanced Non–Small-Cell Lung Cancer

George R. Blumenschein, U. Gatzemeier, Frank V. Fossella et al. · Journal of Clinical Oncology · 2009 · 204 citations · Full text

Medicine, Oncology, Pharmacology +16