Concepedia

N.T. Schirle

NS

12

Publications

2.1K

Citations

11

H-Index

2008

Active since

Affiliations

Scripps Research Institute(Current)

University of California, Davis

Delft University of Technology

N.T. Schirle is an author at Scripps Research Institute specializing in medicine, gene expression, and molecular biology.

Top concepts

MedicineGene ExpressionMolecular BiologyNatural SciencesNon-coding RnaSystems BiologyGenome EditingGeneticsRna BiologyBioinformatics

Publications per year

2008–2019

12

Publications

12

The Crystal Structure of Human Argonaute2

N.T. Schirle, Ian J. MacRae · Science · 2012 · 698 citations

X-ray Crystallography, Human Argonaute2, Tandem Tryptophan-binding Pockets +15

Structural basis for microRNA targeting

N.T. Schirle, Jessica Sheu‐Gruttadauria, Ian J. MacRae · Science · 2014 · 568 citations · Full text

Bioinformatics, Natural Sciences, Genetics +12

A Dynamic Search Process Underlies MicroRNA Targeting

Stanley D. Chandradoss, N.T. Schirle, Malwina Szczepaniak et al. · Cell · 2015 · 258 citations · Full text

Functional Genomics, Genetics, Microrna Detection +5

RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1

Jongchan Yeo, Rena A. Goodman, N.T. Schirle et al. · Proceedings of the National Academy of Sciences · 2010 · 181 citations · Full text

In Vivo Gene Therapy, Genetics, Molecular Biology +17

Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets

N.T. Schirle, Jessica Sheu‐Gruttadauria, Stanley D. Chandradoss et al. · eLife · 2015 · 103 citations · Full text

Human Argonaute2, Transcriptional Regulation, Direct Post-transcriptional Regulation +13

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