Brian K. Mannakee

Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding

William M. Holmes, Brian K. Mannakee, Ryan N. Gutenkunst et al. · Nature Communications · 2014 · 115 citations · Full text

Protein Function, Prion Phenotype, Amino-terminal Acetylation +10

Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility

Erik S. Knudsen, Uthra Balaji, Brian K. Mannakee et al. · Gut · 2017 · 103 citations · Full text

Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeast

Russell A. Hermansen, Brian K. Mannakee, Wolfgang Knecht et al. · BMC Evolutionary Biology · 2015 · 17 citations · Full text

Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an N-of-1 clinical trial

Montaser Shaheen, Julie Y. Tse, Ethan Sokol et al. · eLife · 2022 · 13 citations · Full text

Testing whether Metazoan Tyrosine Loss Was Driven by Selection against Promiscuous Phosphorylation

S. H. Pandya, Travis J. Struck, Brian K. Mannakee et al. · Molecular Biology and Evolution · 2014 · 11 citations · Full text

Genetics, Genomic Mechanism, Promiscuous Phosphorylation +22