Gerard J. P. van Westen

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason et al. · Nature Communications · 2019 · 350 citations · Full text

Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set

Eelke B. Lenselink, Niels ten Dijke, Brandon J. Bongers et al. · Journal of Cheminformatics · 2017 · 328 citations · Full text

Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness

Alexander V. Lebedev, Eric Westman, Gerard J. P. van Westen et al. · NeuroImage Clinical · 2014 · 316 citations · Full text

Proteochemometric modeling as a tool to design selective compounds and for extrapolating to novel targets

Gerard J. P. van Westen, Jörg K. Wegner, Adriaan P. IJzerman et al. · MedChemComm · 2010 · 173 citations

Combinatorial Chemistry, Engineering, Chemical Analysis +19

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

Ping Li, Daniel Rial, Paula M. Canas et al. · Molecular Psychiatry · 2015 · 137 citations · Full text

Impair Memory, Neurophysiology, Medicine +11