Jay S. Dela Cruz

Recombinant Anti-Human HER2/ <i>neu</i> IgG3-(GM-CSF) Fusion Protein Retains Antigen Specificity and Cytokine Function and Demonstrates Antitumor Activity

Jay S. Dela Cruz, K. Ryan Trinh, Sherie L. Morrison et al. · The Journal of Immunology · 2000 · 83 citations · Full text

An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells

Patrick P. Ng, Jay S. Dela Cruz, David N. Sorour et al. · Proceedings of the National Academy of Sciences · 2002 · 78 citations · Full text

Immunology, Cell Death, Immunologic Mechanism +22

Protein vaccination with the HER2/neu extracellular domain plus anti-HER2/neu antibody–cytokine fusion proteins induces a protective anti-HER2/neu immune response in mice

Jay S. Dela Cruz, Suk Ying Lau, Ernesto M Ramirez et al. · Vaccine · 2003 · 61 citations

Vaccination, Cross-protection, Protein Vaccination +14

A recombinant IgG3-(IL-2) fusion protein for the treatment of human HER2/neu expressing tumors

Manuel L. Penichet, Jay S. Dela Cruz, Seung-Uon Shin et al. · Human Antibodies · 2001 · 42 citations

Radiation Oncology, Cancer Immunosurveillance, Anti-her2/neu Igg3- +15

Vaccination with novel combinations of anti-HER2/neu cytokines fusion proteins and soluble protein antigen elicits a protective immune response against HER2/neu expressing tumors

Gustavo Helguera, Jay S. Dela Cruz, Christine Lowe et al. · Vaccine · 2005 · 25 citations

Vaccination, Protective Immune Response, Immunology +10