Guo‐Chao Chu

H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity

Huasong Ai, Maoshen Sun, Aijun Liu et al. · Nature Chemical Biology · 2022 · 110 citations

Chromatin, Signal Transduction, Chromatin Structure +11

Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones

Guo‐Chao Chu, Man Pan, Jiabin Li et al. · Journal of the American Chemical Society · 2019 · 96 citations

Chemical Synthesis of Activity‐Based E2‐Ubiquitin Probes for the Structural Analysis of E3 Ligase‐Catalyzed Transthiolation

Lujun Liang, Guo‐Chao Chu, Qian Qu et al. · Angewandte Chemie International Edition · 2021 · 80 citations

Combinatorial Chemistry, Engineering, Protein Assembly +20

Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes

Huasong Ai, Guo‐Chao Chu, Qingyue Gong et al. · Journal of the American Chemical Society · 2022 · 65 citations

Histone Modifications, Epigenetic Change, Molecular Biology +17

Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins

Baochang Zhang, Yupeng Zheng, Guo‐Chao Chu et al. · Angewandte Chemie International Edition · 2023 · 52 citations · Full text