Mehdi Derhourhi

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension

Morgane Baron, Julie O’Sullivan Maillet, Marlène Huyvaert et al. · Nature Medicine · 2019 · 91 citations · Full text

Obesity, Metabolic Syndrome, Metabolic Disorder +11

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity

Wenwen Gao, Lei Liu, Eunna Huh et al. · Nature Metabolism · 2023 · 38 citations · Full text

Obesity, Metabolic Syndrome, Insulin Signaling +11

Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan

Sadia Saeed, Muhammad Arslan, Jaida Manzoor et al. · Diabetes · 2020 · 31 citations

Genetic Causes, Metabolic Disorder, Genetics +22

Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study

Lise Folon, Morgane Baron, Bénédicte Toussaint et al. · The Lancet Diabetes & Endocrinology · 2023 · 30 citations · Full text

Obesity, Metabolic Syndrome, Metabolic Disorder +7

Heterozygous pathogenic variants in POMC are not responsible for monogenic obesity: Implication for MC4R agonist use

Lauriane Le Collen, Brigitte Delemer, Christine Poitou et al. · Genetics in Medicine · 2023 · 20 citations · Full text

Obesity, Metabolic Syndrome, Metabolic Disorder +11