P. J. M. Klippert

Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data — correlation with in in vivo data using mucosal blood flow

P. J. M. Klippert, Paul Borm, J. Noordhoek · Biochemical Pharmacology · 1982 · 38 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Determination of ivabradine and its N-demethylated metabolite in human plasma and urine, and in rat and dog plasma by a validated high-performance liquid chromatographic method with fluorescence detection

P. J. M. Klippert, Jean-Philippe Jeanniot, Sabine Polvé et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1998 · 37 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Isolation and identification of mercapturic acids of cinnamic aldehyde and cinnamyl alcohol from urine of female rats

L. P. C. Delbressine, P. J. M. Klippert, J. T. A. Reuvers et al. · Archives of Toxicology · 1981 · 30 citations

Pharmacy, Biochemistry, Toxicology +6

In vivo O-de-ethylation of phenacetin in 3-methylcholanthrene-pretreated rats: gut wall and liver first-pass metabolism.

P. J. M. Klippert, R J Littel, J. Noordhoek · Journal of Pharmacology and Experimental Therapeutics · 1983 · 22 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Low oral bioavailability of hexamethylmelamine in the rat due to simultaneous hepatic and intestinal metabolism.

P. J. M. Klippert, A. Hulshoff, Marie-José J. Mingels et al. · PubMed · 1983 · 19 citations

Pharmacy, Pharmacokinetics, Pharmacology +17