Mitsuharu Hanada

Disruption of the gene encoding p12 (SecG) reveals the direct involvement and important function of SecG in the protein translocation of Escherichia coli at low temperature.

Kenichi Nishiyama, Mitsuharu Hanada, Haruhiko Tokuda · The EMBO Journal · 1994 · 170 citations · Full text

Life Sciences, Microbiology, Molecular Biology +9

Reconstitution of an efficient protein translocation machinery comprising SecA and the three membrane proteins, SecY, SecE, and SecG (p12).

Mitsuharu Hanada, Kenichi Nishiyama, San-ichiro Mizushima et al. · Journal of Biological Chemistry · 1994 · 126 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

A New Antitumor Agent Amrubicin Induces Cell Growth Inhibition by Stabilizing Topoisomerase II‐DNA Complex

Mitsuharu Hanada, Satoko Mizuno, Akihisa Fukushima et al. · Japanese Journal of Cancer Research · 1998 · 107 citations · Full text

Medicine, Oncology, Pharmacology +16

Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis

Mitsuharu Hanada, Akemi Baba, Yasuyuki Tsutsumishita et al. · Cancer Chemotherapy and Pharmacology · 2008 · 61 citations · Full text

Medicine, Oncology, Pharmacology +17

SecG plays a critical role in protein translocation in the absence of the proton motive force as well as at low temperature

Mitsuharu Hanada, Kenichi Nishiyama, Hajime Tokuda · FEBS Letters · 1996 · 42 citations

Life Sciences, Biochemistry, Molecular Biology +10