J. Samuel Tolman

Publications

Citations

H-Index

2000

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

J. Samuel Tolman is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, alpha-adrenergic pharmacology, and pharmacotherapy.

Top concepts

MedicinePharmacologyDrug DiscoveryPharmacotherapyMolecular PharmacologyAlpha-adrenergic PharmacologyPhysiologyBiochemistryDrug Development

Publications per year

2000–2000

Publications

Discovery of a Potent, Orally Bioavailable β3 Adrenergic Receptor Agonist, (R)-N-[4-[2-[[2-Hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide

Robert J. Mathvink, J. Samuel Tolman, Dawn Chitty et al. · Journal of Medicinal Chemistry · 2000 · 63 citations · Full text

Molecular Pharmacology, Pharmaceutical Science, Substituted Thiazole Benzenesulfonamide +15

Potent, selective 3-pyridylethanolamine β3 adrenergic receptor agonists possessing a thiazole benzenesulfonamide pharmacophore

Robert J. Mathvink, J. Samuel Tolman, Dawn Chitty et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 22 citations · Full text

Molecular Pharmacology, Medicine, Thiazole Benzenesulfonamide Pharmacophore +6

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