Jon I. Williams

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature.

Allen K. Sills, Jon I. Williams, Betty Tyler et al. · PubMed · 1998 · 169 citations

Medicine, Oncology, Pharmacology +12

Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na⁺/H⁺exchanger isoform NHE3

Shafinaz Akhter, S. Nath, Chung‐Ming Tse et al. · American Journal of Physiology-Cell Physiology · 1999 · 133 citations

Life Sciences, Biochemistry, Pharmacology +7

Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression

Dan Li, Jon I. Williams, Richard J. Pietras · Oncogene · 2002 · 82 citations

Medicine, Oncology, Pharmacology +16

A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers.

Pankaj Bhargava, J L Marshall, William Dahut et al. · PubMed · 2001 · 81 citations

Medicine, Oncology, Pharmacology +17

Deoxyribonucleic acid excision repair in chromatin after ultraviolet irradiation of human fibroblasts in culture

Jon I. Williams, E C Friedberg · Biochemistry · 1979 · 79 citations

Life Sciences, Genetics, Molecular Biology +16