Seong Hoong Chow

Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

Pankaj Deo, Seong Hoong Chow, Mei‐Ling Han et al. · Nature Microbiology · 2020 · 224 citations

Inflammation, Mitophagy, Gram-negative Bacteriology +11

Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

Pankaj Deo, Seong Hoong Chow, Iain D. Hay et al. · PLoS Pathogens · 2018 · 139 citations · Full text

Innate Immune System, Immunology, Cell Death +18

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

Daniel S. Simpson, Jiyi Pang, Ashley Weir et al. · Immunity · 2022 · 129 citations · Full text

Inflammation, Cytokine, Interferon-γ Primes Macrophages +11

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis

Mary Speir, Kate E. Lawlor, Stefan Glaser et al. · Nature Microbiology · 2016 · 75 citations

Medical Microbiology, Macrophage Apoptosis, Immunology +5

Polymyxin-Induced Lipid A Deacylation in <i>Pseudomonas aeruginosa</i> Perturbs Polymyxin Penetration and Confers High-Level Resistance

Mei‐Ling Han, Tony Velkov, Yan Zhu et al. · ACS Chemical Biology · 2017 · 63 citations

Polymyxin Resistance, Antimicrobial Resistance Gene, Antimicrobial Susceptibility +14