Meredith E. Jackrel

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

Lin Guo, Hong Joo Kim, Hejia Wang et al. · Cell · 2018 · 467 citations · Full text

Natural Sciences, Rna Binding Proteins, Rna Structure Prediction +8

Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104

Stephanie N. Gates, Adam L. Yokom, JiaBei Lin et al. · Science · 2017 · 271 citations · Full text

Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events

Meredith E. Jackrel, Morgan E. DeSantis, Bryan Martinez et al. · Cell · 2014 · 235 citations · Full text

Natural Sciences, Molecular Biology, Proteomics +2

Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid and Nonamyloid Clients

Morgan E. DeSantis, Eunice H. Leung, Elizabeth A. Sweeny et al. · Cell · 2012 · 178 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Protein Folding +9

Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation

Adam L. Yokom, Stephanie N. Gates, Meredith E. Jackrel et al. · Nature Structural & Molecular Biology · 2016 · 114 citations · Full text

Polypeptide Translocation, Hsp104 Disaggregase, Protein Function +10