Alexander Vargas‐Hernández

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Joshua D. Milner, Tiphanie P. Vogel, Lisa R. Forbes et al. · Blood · 2014 · 556 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

Jennifer W. Leiding, Tiphanie P. Vogel, Valentine G.J. Santarlas et al. · Journal of Allergy and Clinical Immunology · 2022 · 124 citations · Full text

Life Sciences, Genetics, Immunology +11

HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease

Sarah A. Cook, William A. Comrie, M. Cecilia Poli et al. · Science · 2020 · 100 citations · Full text

Life Sciences, Genetics, Immunology +17

Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations

Alexander Vargas‐Hernández, Emily M. Mace, Ofer Zimmerman et al. · Journal of Allergy and Clinical Immunology · 2017 · 96 citations

Life Sciences, Immunology, Molecular Biology +14

First Report of the Hyper-IgM Syndrome Registry of the Latin American Society for Immunodeficiencies: Novel Mutations, Unique Infections, and Outcomes

Otávio Cabral-Marques, Stefanie Klaver, Lena F. Schimke et al. · Journal of Clinical Immunology · 2014 · 83 citations · Full text

Life Sciences, Immunology, Internal Medicine +17