Systems Pharmacology Approach for Prediction of Pulmonary and Systemic Pharmacokinetics and Receptor Occupancy of Inhaled Drugs

Elin Boger, Neil D. Evans, M.J. Chappell, +4

CPT Pharmacometrics & Systems Pharmacology

Controlled Pulmonary Delivery of Carrier-Free Budesonide Dry Powder by Atomic Layer Deposition

Damiano La Zara, Feilong Sun, Fuweng Zhang, +10

ACS Nano

A Novel Method to Aerosolize Powder for Short Inhalation Exposures at High Concentrations: Isolated Rat Lungs Exposed to Respirable Diesel Soot

Per Gerde, Pär Ewing, Lena Låstbom, +3

Inhalation Toxicology

Dissolv <i>It</i> : An <i>In Vitro</i> Method for Simulating the Dissolution and Absorption of Inhaled Dry Powder Drugs in the Lungs

Per Gerde, Maria Malmlöf, Lina Havsborn, +4

Assay and Drug Development Technologies

Development of a Novel Lung Slice Methodology for Profiling of Inhaled Compounds

Erica Bäckström, Anders Lundqvist, Elin Boger, +4

Journal of Pharmaceutical Sciences

AsthmaLung DepositionRespiratory ToxicologyMedicineBioanalysis +10

Polyethylene glycol-drug ester conjugates for prolonged retention of small inhaled drugs in the lung

Fabrice J. C. Bayard, Wim Thielemans, David Pritchard, +5

Journal of Controlled Release

Pharmaceutical ScienceMpeg₂₀₀₀ ConjugatesSmall Inhaled DrugsPharmacotherapyPrednisolone Concentrations +16

Dry Powder Inhalation Exposures of the Endotracheally Intubated Rat Lung, <i>Ex Vivo</i> and <i>In Vivo</i> : The Pulmonary Pharmacokinetics of Fluticasone Furoate

Ewa Selg, Pär Ewing, Fernando Acevedo, +3

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Aggregates of ultrafine particles modulate lipid peroxidation and bacterial killing by alveolar macrophages

Margot Lundborg, Rabea K.L. Bouhafs, Per Gerde, +4

Environmental Research

InflammationUltrafine ParticlesBiochemistryLung InflammationLipid Peroxidation +5

Pulmonary Metabolism of Substrates for Key Drug-Metabolizing Enzymes by Human Alveolar Type II Cells, Human and Rat Lung Microsomes, and the Isolated Perfused Rat Lung Model

Katarina Rubin, Pär Ewing, Erica Bäckström, +4

Pharmaceutics

Lung InflammationPulmonary MetabolismRat Lung ModelMolecular PharmacologyRespiratory Toxicology +17

A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships

Elin Boger, Pär Ewing, Ulf G. Eriksson, +4

Journal of Pharmacology and Experimental Therapeutics