Thomas S. O’Leary

Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy

Michael J. Previs, Thomas S. O’Leary, Michael P. Morley et al. · Circulation Heart Failure · 2022 · 99 citations · Full text

Life Sciences, Biochemistry, Cardiology +13

Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy

Adam Helms, Vi T. Tang, Thomas S. O’Leary et al. · JCI Insight · 2019 · 97 citations · Full text

Medicine, Cardiology, Genetics +11

MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy

Thomas S. O’Leary, Julia P Snyder, Sakthivel Sadayappan et al. · Journal of Molecular and Cellular Cardiology · 2018 · 66 citations · Full text

Life Sciences, Cardiology, Molecular Biology +16

Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems

Amy Li, Shane R. Nelson, Sheema Rahmanseresht et al. · Proceedings of the National Academy of Sciences · 2019 · 56 citations · Full text

Life Sciences, Molecular Biology, Physiology +17

Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster

Melise C. Lecheta, David N. Awde, Thomas S. O’Leary et al. · Frontiers in Genetics · 2020 · 55 citations · Full text

Life Sciences, Biology, Genetics +17