Julien Robert‐Paganin

Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil

Vicente J. Planelles-Herrero, James J. Hartman, Julien Robert‐Paganin et al. · Nature Communications · 2017 · 210 citations · Full text

Natural Sciences, Biochemistry, Biophysics +17

Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

Julien Robert‐Paganin, Daniel Auguin, Anne Houdusse · Nature Communications · 2018 · 120 citations · Full text

Natural Sciences, Biophysics, Cardiology +17

Cryo-EM structure of the folded-back state of human β-cardiac myosin

Alessandro Grinzato, Daniel Auguin, Carlos Kikuti et al. · Nature Communications · 2023 · 70 citations · Full text

Life Sciences, Biophysics, Molecular Biology +17

Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

Julien Robert‐Paganin, James P. Robblee, Daniel Auguin et al. · Nature Communications · 2019 · 64 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy

James J. Hartman, Darren T. Hwee, Julien Robert‐Paganin et al. · Nature Cardiovascular Research · 2024 · 58 citations · Full text

Life Sciences, Biology, Cardiology +17