Philip D. Kiser

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

Susie Suh, Elliot H. Choi, Henri Leinonen et al. · Nature Biomedical Engineering · 2020 · 167 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

Philip D. Kiser, Marcin Golczak, David T. Lodowski et al. · Proceedings of the National Academy of Sciences · 2009 · 160 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

Marcin Golczak, Akiko Maeda, Grzegorz Bereta et al. · Journal of Biological Chemistry · 2008 · 92 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Catalytic mechanism of a retinoid isomerase essential for vertebrate vision

Philip D. Kiser, Jianye Zhang, Mohsen Badiee et al. · Nature Chemical Biology · 2015 · 83 citations · Full text

Life Sciences, Molecular Biology, Vision Science +15

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Sahil Gulati, Hui Jin, Ikuo Masuho et al. · Nature Communications · 2018 · 82 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15