Tom T. Lee

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy

Frank Cichocki, Ryan Bjordahl, Svetlana Gaidarova et al. · Science Translational Medicine · 2020 · 235 citations · Full text

Cell Therapy, Immunology, Nk Cells +19

Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy

Karrune Woan, Hansol Kim, Ryan Bjordahl et al. · Cell stem cell · 2021 · 147 citations · Full text

Cell Therapy, Adaptive Nk Cells, Adaptive Immune System +9

A Unique RNA Fold in the RumA-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function

Tom T. Lee, Sanjay Agarwalla, R. M. Stroud · Cell · 2005 · 103 citations · Full text

Substrate Selectivity, Unique Rna Fold, Biochemistry +10

Structure of a TrmA–RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m ⁵ U methyltransferases

Akram Alian, Tom T. Lee, Sarah L. Griner et al. · Proceedings of the National Academy of Sciences · 2008 · 85 citations · Full text

Nucleic Acid Chemistry, Engineering, Biochemistry +12

Dual antigen–targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia

Frank Cichocki, Jodie P. Goodridge, Ryan Bjordahl et al. · Blood · 2022 · 79 citations · Full text