Essential Requirement for PP2A Inhibition by the Oncogenic Receptor c-KIT Suggests PP2A Reactivation as a Strategy to Treat c-KIT+ Cancers

Kathryn G. Roberts, Amanda M. Smith, Fiona McDougall, +10

Cancer Research

Novel mutations of the growth hormone 1 (GH1) gene disclosed by modulation of the clinical selection criteria for individuals with short stature

David S. Millar, Mark Lewis, Martin Horan, +16

Human Mutation

Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 ( <i>NF1</i> ) gene in neurofibromatosis patients with benign and malignant tumors

Meena Upadhyaya, Song Han, Claudia Consoli, +8

Human Mutation

GeneticsPathologyGliomaTumor BiologyNeuro-oncology +15

Human growth hormone 1 (<i>GH1</i>) gene expression: Complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region

Martin Horan, David Millar, Jürgen Hedderich, +7

Human Mutation

Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts

Nady Braidy, Wei‐Ping Gai, Ying Xu, +8

Translational Neurodegeneration

A Novel Dysfunctional Growth Hormone Variant (Ile179Met) Exhibits a Decreased Ability to Activate the Extracellular Signal-Regulated Kinase Pathway

Mark Lewis, Martin Horan, David Millar, +15

The Journal of Clinical Endocrinology & Metabolism

Characterisation of a functional intronic polymorphism in the human growth hormone (GHI) gene

David Millar, Martin Horan, Nadia Chuzhanova, +1

Human Genomics

The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice

David G. Le Couteur, Szun S. Tay, Samantha M. Solon‐Biet, +15

The Journals of Gerontology Series A

NutritionAgingAging MiceImmunologyImmune Regulation +20

Hypermethylation of the neurofibromatosis type 1 (NF1) gene promoter is not a common event in the inactivation of the NF1 gene in NF1-specific tumours

Martin Horan, D.N. Cooper, Meena Upadhyaya

Human Genetics

Neuro-oncologyTumor InnervationNf1 GenePathologyNf1-specific Tumours +6

Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke

Martin Horan, Vicky Newsway, Yasmin Yasmin, +15

Human Genetics

Metabolic SyndromeHypertensionGenetic DeterminantGrowth HormoneGenetics +13