Target-Based Approach to Inhibitors of Histone Arginine Methyltransferases

Astrid Spannhoff, Ralf Heinke, Ingo Bauer, +7

Journal of Medicinal Chemistry

Histone ModificationsDrug TargetEpigenetic ChangeChemical BiologyEpigenetics +16

Internalization of hydroxyapatite nanoparticles in liver cancer cells

Ingo Bauer, Shipu Li, Yingchao Han, +2

Journal of Materials Science Materials in Medicine

NanoparticlesNanomedicineEngineeringHydroxyapatiteHydroxyapatite Nanoparticles +3

Small Molecule Inhibitors of Histone Arginine Methyltransferases:  Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluations

Rino Ragno, Silvia Simeoni, Sabrina Castellano, +9

Journal of Medicinal Chemistry

Histone ModificationsSmall Molecule InhibitorsDrug TargetBioorganic ChemistryEpigenetic Change +23

A novel arginine methyltransferase inhibitor with cellular activity

Astrid Spannhoff, Rospita Machmur, Ralf Heinke, +7

Bioorganic & Medicinal Chemistry Letters

Cellular ActivityMedicineCellular PharmacologyAntisense TherapyPharmacology +2

Virtual Screening and Biological Characterization of Novel Histone Arginine Methyltransferase PRMT1 Inhibitors

Ralf Heinke, Astrid Spannhoff, René Meier, +4

ChemMedChem

Histone ModificationsDrug TargetEpigenetic ChangeGeneticsMolecular Biology +23

Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI‐1)

Sabrina Castellano, Ciro Milite, Rino Ragno, +10

ChemMedChem

A Novel Motif in Fungal Class 1 Histone Deacetylases Is Essential for Growth and Development of<i>Aspergillus</i>

Martin Tribus, Ingo Bauer, Johannes Galehr, +6

Molecular Biology of the Cell

Histone DeacetylasesFungal Cell BiologyMolecular BiologyMolecular GeneticsChemical Biology +15

Sonochemical preparation of hydroxyapatite nanoparticles stabilized by glycosaminoglycans

Yingchao Han, Shipu Li, Xinyu Wang, +2

Ultrasonics Sonochemistry

EngineeringHydroxyapatiteHydroxyapatite NanoparticlesBioceramicBiomedical Engineering +2

A Class 1 Histone Deacetylase as Major Regulator of Secondary Metabolite Production in Aspergillus nidulans

Angelo Pidroni, Birgit Faber, Gerald Brosch, +2

Frontiers in Microbiology

A Class 1 Histone Deacetylase with Potential as an Antifungal Target

Ingo Bauer, Divyavaradhi Varadarajan, Angelo Pidroni, +7

mBio